Microbeams: a potent mix of physics and biology. Summary of the 5th International Workshop on Microbeam Probes of Cellular Radiation Response.

نویسندگان

  • D J Brenner
  • E J Hall
چکیده

Single-cell microbeam irradiators are of increasing interest to the biological community. The 5th International Workshop on Microbeam Probes of Cellular Radiation Response, which took place in Stresa, Italy, in May 2001, was attended by about 120 registrants, roughly evenly divided between physicists and biologists. Many new microbeam devices are now under development, and there has been a significant diversification of the biological questions addressed. Most current uses of microbeams have been to address radiobiological questions, but the advent of sub-micrometre targeting capabilities, and the development of new single-cell assays, point to the potential for microbeams to make an important contribution to biological, and not just radiobiological, studies.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Deflection of a hyperbolic shear deformable microbeam under a concentrated load

Deflection analysis of a simply supported microbeam subjected to a concentrated load at the middle is investigated on the basis of a shear deformable beam theory and non-classical theory. Effects of shear deformation and small size are taken into consideration by hyperbolic shear deformable beam theory and modified strain gradient theory, respectively. The governing differential equations and c...

متن کامل

Free Vibration Analysis of Nonuniform Microbeams Based on Modified Couple Stress Theory: an Analytical Solution

In this study, analytical solution is presented to calculate the free vibration frequencies of nonuniform microbeams. Scale effects are modelled using modified couple stress theory and the microbeam is assumed to be thin while Poisson's ratio effects are also taken into account. Nonuniformity is presented by exponentially varying width among the microbeam while the thickness remains constant. R...

متن کامل

A charged-particle microbeam: I. Development of an experimental system for targeting cells individually with counted particles.

Charged-particle microbeams provide a unique opportunity to control precisely, the dose to individual cells and the localization of dose within the cell. The Gray Laboratory is now routinely operating a charged-particle microbeam capable of delivering targeted and counted particles to individual cells, at a dose-rate sufficient to permit a number of single-cell assays of radiation damage to be ...

متن کامل

Effect of temperature on free vibration of functionally graded microbeams

Modified couple stress theory is applied to study of temperature effects on free vibration of Timoshenko functionally graded microbeams. Due to the interatomic and microstructural reactions of the structures in micro scale, the dynamic behavior of the microbeam is predicted more accurate applying the couple stress theory. Both of the simply supported and clamped boundary conditions are assumed ...

متن کامل

Cellular response to ionizing radiation: A microRNA story

MicroRNAs (miRNAs) represent a class of small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They play a crucial role in diverse cellular pathways. Ionizing radiation (IR) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. Recently it has been discovered that mi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Radiation protection dosimetry

دوره 99 1-4  شماره 

صفحات  -

تاریخ انتشار 2002